water quality · both tank

Ammonia Poisoning

Ammonia poisoning happens when NH3/NH4+ levels exceed 0.25 ppm and damage fish gill tissue + nervous system. The single fastest way to lose a tank.

Reviewed by Fast Aquatics husbandry team · Updated May 2026
Severity: CRITICAL - hours from problem to mass die-off

Symptoms

What causes it

Filter failure, tank crash, dead specimen decomposing, overfeeding, replacing too much filter media at once, or a new tank that hasn't cycled.

Treatment options

Always treat in a separate quarantine tank.

Immediate water change. 50% water change with dechlorinated, parameter-matched water. Continue 25% daily until ammonia is 0.
Seachem Prime. Prime detoxifies ammonia for 24-48 hours by binding it to a less-toxic form. Use as a bridge while water changes are done. Standard dose every 24 hours during outbreak.
Stop feeding. No food for 3-5 days. Reduces bio-load while the cycle re-establishes.

Prevention

Test ammonia weekly. Don't replace filter media all at once. Don't overstock or overfeed.

Frequently asked questions

What does Ammonia Poisoning look like?

Gasping at the surface. Red or inflamed gills. Lethargy and laying on the bottom.

What causes Ammonia Poisoning?

Filter failure, tank crash, dead specimen decomposing, overfeeding, replacing too much filter media at once, or a new tank that hasn't cycled.

How is Ammonia Poisoning treated?

Immediate water change: 50% water change with dechlorinated, parameter-matched water. Continue 25% daily until ammonia is 0.

Can Ammonia Poisoning be prevented?

Test ammonia weekly. Don't replace filter media all at once. Don't overstock or overfeed.

How fatal is Ammonia Poisoning?

CRITICAL - hours from problem to mass die-off

Related

Browse the full disease database for 45 aquarium conditions with treatment protocols, or check the care library for prevention-focused husbandry guides. Use our symptom matcher to rank likely diseases from observed signs, the water parameter checker to diagnose related water-quality issues, or the QT timeline calculator to plan a treatment schedule.